|
|
Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us |
|
PolysacDB ID | 1259 |
Carbohydrate Name | O-polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Campylobacter fetus 554 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen) |
BCSDB Structure | N/A |
Proposed functions | The LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme |
Antigenic Nature used to produce antibodies | A mixture (1:1) of C. fetus 553 and 554 formalin-killed cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab M1177 |
Antibody type and class | IgG1 |
Assay System | Indirect ELISA, immunoblotting, |
Cross-reactivity | This antibody was specific to O antigen of C. fetus 554 and did not cross-react with C. fetus 553 |
Proposed epitopes | Acetylated groups seem to be an important part of the epitope |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used to serotype C. fetus strains |
Curator ID | AA + AS |
Date of Curation | 28-04-2010 |
References | PMC98852 |
PolysacDB ID | 1260 |
Carbohydrate Name | O-polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Campylobacter fetus 554 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen) |
BCSDB Structure | N/A |
Proposed functions | The LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme |
Antigenic Nature used to produce antibodies | A mixture (1:1) of C. fetus 553 and 554 formalin-killed cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab M1194 |
Antibody type and class | IgG1 |
Assay System | Indirect ELISA, immunoblotting, |
Cross-reactivity | This antibody was specific to O antigen of C. fetus 554 and did not cross-react with C. fetus 553 |
Proposed epitopes | Acetylated groups do not seem to be a part of the epitope |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used to serotype C. fetus strains |
Curator ID | AA + AS |
Date of Curation | 01-05-2010 |
References | PMC98852 |
PolysacDB ID | 1261 |
Carbohydrate Name | O-polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Campylobacter fetus 554 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen) |
BCSDB Structure | N/A |
Proposed functions | The LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme |
Antigenic Nature used to produce antibodies | A mixture (1:1) of C. fetus 553 and 554 formalin-killed cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab M1183 |
Antibody type and class | IgG1 |
Assay System | Indirect ELISA, immunoblotting, |
Cross-reactivity | This antibody was specific to O antigen of C. fetus 553 and did not cross-react with C. fetus 554 |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used to serotype C. fetus strains |
Curator ID | AA + AS |
Date of Curation | 02-05-2010 |
References | PMC98852 |
Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |