PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 3

Entry No. - 1   [TOP]
PolysacDB ID1228
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeBrucella abortus biotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureLPS carries the A (B. abortus-type) and M (B. melitensis-type) epitopes, respectively. In addition, there is at least one common (C) epitope restricted to the smooth brucellae and a second common epitope (C/Y) shared with Yersinia enterocolitica O:9
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesCattle polysera
Antibody type and classN/A
Assay SystemInihibitory ELISA
Cross-reactivityThis antibody reacted with both crude LPS and the native hapten component of Brucella
Proposed epitopesThe epitope was proposed to consist of A and C epitopes
IEDB Epitope76804
Proposed UtilityThis antisera can be used for the diagnosis of brucellosis in small ruminants and cattle
Curator IDAA + AS
Date of Curation26-03-2010
ReferencesPMC96196


Entry No. - 2   [TOP]
PolysacDB ID1229
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeBrucella abortus biotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureLPS carries the A (B. abortus-type) and M (B. melitensis-type) epitopes, respectively. In addition, there is at least one common (C) epitope restricted to the smooth brucellae and a second common epitope (C/Y) shared with Yersinia enterocolitica O:9
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesGoat polysera
Antibody type and classN/A
Assay SystemInihibitory ELISA
Cross-reactivityThis antibody reacted with both crude LPS and the native hapten component of Brucella
Proposed epitopesThe epitope was proposed to consist of A and C epitopes
IEDB Epitope76804
Proposed UtilityThis antisera can be used for the diagnosis of brucellosis in small ruminants and cattle
Curator IDAA + AS
Date of Curation26-03-2010
ReferencesPMC96196


Entry No. - 3   [TOP]
PolysacDB ID1230
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeBrucella abortus biotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureLPS carries the A (B. abortus-type) and M (B. melitensis-type) epitopes, respectively. In addition, there is at least one common (C) epitope restricted to the smooth brucellae and a second common epitope (C/Y) shared with Yersinia enterocolitica O:9
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesSheep antisera
Antibody type and classN/A
Assay SystemInihibitory ELISA
Cross-reactivityThis antibody reacted with both crude LPS and the native hapten component of Brucella
Proposed epitopesThe epitope was proposed to consist of A and C epitopes
IEDB Epitope76804
Proposed UtilityThis antisera can be used for the diagnosis of brucellosis in small ruminants and cattle
Curator IDAA + AS
Date of Curation26-03-2010
ReferencesPMC96196


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