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| PolysacDB ID | 1172 |
| Carbohydrate Name | Lipoologosaccharide band A of the LPS (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Bordetella pertusis 9340 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | B. pertusis LPS is resolved electrophoretically into two bands, a slowly migrating band designated LOS A and a fast-migrating band designated LOS B. These two species differ in molecular weight as three N-acetyl amino sugars found on LOS A are not present on LOS B |
| BCSDB Structure | N/A |
| Proposed functions | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature used to produce antibodies | N-Lauroyl sarcosine membrane extract (SME) from B. pertussis 9340 |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab BL-1 |
| Antibody type and class | IgG1 |
| Assay System | ELISA,immunoblotting, Antibody accessibility radioimmunoassay, bactericidal asaay, competitive ELISA |
| Cross-reactivity | This antibody reacted with all B.pertusis strains, did not react with B. parapertusis or other gram negative bacteria but cross-reacted with 4 B. bronchiseptica strains which had LOS AB phenotype |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was capable of inducing bactericidal activity in uitro. |
| Curator ID | AA + AS |
| Date of Curation | 25-02-2010 |
| References | 1713258 |
| PolysacDB ID | 1173 |
| Carbohydrate Name | Lipoologosaccharide band A of the LPS (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Bordetella pertusis 9340 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | B. pertusis LPS is resolved electrophoretically into two bands, a slowly migrating band designated LOS A and a fast-migrating band designated LOS B. These two species differ in molecular weight as three N-acetyl amino sugars found on LOS A are not present on LOS B |
| BCSDB Structure | N/A |
| Proposed functions | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature used to produce antibodies | N-Lauroyl sarcosine membrane extract (SME) from B. pertussis 9340 |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab BL-3 |
| Antibody type and class | IgM |
| Assay System | ELISA,immunoblotting, Antibody accessibility radioimmunoassay, bactericidal asaay, competitive ELISA |
| Cross-reactivity | This antibody reacted with all B.pertusis strains, did not react with B. parapertusis or other gram negative bacteria but cross-reacted with 4 B. bronchiseptica strains which had LOS AB phenotype |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was capable of inducing bactericidal activity in uitro. |
| Curator ID | AA + AS |
| Date of Curation | 25-02-2010 |
| References | 1713258 |
| PolysacDB ID | 1174 |
| Carbohydrate Name | Lipoologosaccharide band A of the LPS (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Bordetella pertusis 9340 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | B. pertusis LPS is resolved electrophoretically into two bands, a slowly migrating band designated LOS A and a fast-migrating band designated LOS B. These two species differ in molecular weight as three N-acetyl amino sugars found on LOS A are not present on LOS B |
| BCSDB Structure | N/A |
| Proposed functions | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature used to produce antibodies | N-Lauroyl sarcosine membrane extract (SME) from B. pertussis 9340 |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab BL-4 |
| Antibody type and class | IgG1 |
| Assay System | ELISA,immunoblotting, Antibody accessibility radioimmunoassay, bactericidal asaay, competitive ELISA |
| Cross-reactivity | This antibody reacted with all B.pertusis strains, did not react with B. parapertusis or other gram negative bacteria but cross-reacted with 4 B. bronchiseptica strains which had LOS AB phenotype |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was capable of inducing bactericidal activity in uitro. |
| Curator ID | AA + AS |
| Date of Curation | 25-02-2010 |
| References | 1713258 |
| PolysacDB ID | 1175 |
| Carbohydrate Name | Lipoologosaccharide band A of the LPS (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Bordetella pertusis 9340 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | B. pertusis LPS is resolved electrophoretically into two bands, a slowly migrating band designated LOS A and a fast-migrating band designated LOS B. These two species differ in molecular weight as three N-acetyl amino sugars found on LOS A are not present on LOS B |
| BCSDB Structure | N/A |
| Proposed functions | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature used to produce antibodies | N-Lauroyl sarcosine membrane extract (SME) from B. pertussis 9340 |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab BL-5 |
| Antibody type and class | IgG1 |
| Assay System | ELISA,immunoblotting, Antibody accessibility radioimmunoassay, bactericidal asaay, competitive ELISA |
| Cross-reactivity | This antibody reacted with all B.pertusis strains, did not react with B. parapertusis or other gram negative bacteria but cross-reacted with 4 B. bronchiseptica strains which had LOS AB phenotype |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was capable of inducing bactericidal activity in uitro. |
| Curator ID | AA + AS |
| Date of Curation | 26-02-2010 |
| References | 1713258 |
| PolysacDB ID | 1176 |
| Carbohydrate Name | Lipoologosaccharide band A of the LPS (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Bordetella pertusis 9340 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | B. pertusis LPS is resolved electrophoretically into two bands, a slowly migrating band designated LOS A and a fast-migrating band designated LOS B. These two species differ in molecular weight as three N-acetyl amino sugars found on LOS A are not present on LOS B |
| BCSDB Structure | N/A |
| Proposed functions | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature used to produce antibodies | N-Lauroyl sarcosine membrane extract (SME) from B. pertussis 9340 |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab BL-6 |
| Antibody type and class | IgG1 |
| Assay System | ELISA,immunoblotting, Antibody accessibility radioimmunoassay, bactericidal asaay, competitive ELISA |
| Cross-reactivity | This antibody reacted with all B.pertusis strains, did not react with B. parapertusis or other gram negative bacteria but cross-reacted with 4 B. bronchiseptica strains which had LOS AB phenotype |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | N/A |
| Curator ID | AA + AS |
| Date of Curation | 26-02-2010 |
| References | 1713258 |
| PolysacDB ID | 1177 |
| Carbohydrate Name | Lipoologosaccharide band A of the LPS (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Bordetella pertusis 9340 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | B. pertusis LPS is resolved electrophoretically into two bands, a slowly migrating band designated LOS A and a fast-migrating band designated LOS B. These two species differ in molecular weight as three N-acetyl amino sugars found on LOS A are not present on LOS B |
| BCSDB Structure | N/A |
| Proposed functions | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature used to produce antibodies | N-Lauroyl sarcosine membrane extract (SME) from B. pertussis 9340 |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab BL-7 |
| Antibody type and class | IgG1 |
| Assay System | ELISA,immunoblotting, Antibody accessibility radioimmunoassay, bactericidal asaay, competitive ELISA |
| Cross-reactivity | This Mab reacted with all B.pertusis strains, did not react with B. parapertusis or other gram negative bacteria but cross-reacted with 4 B. bronchiseptica strains which had LOS AB phenotype |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | N/A |
| Curator ID | AA + AS |
| Date of Curation | 27-02-2010 |
| References | 1713258 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |