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| PolysacDB ID | 1504 |
| Carbohydrate Name | O-polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype b strain 81-750 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues. |
| BCSDB Structure | N/A |
| Proposed functions | LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus |
| Antigenic Nature used to produce antibodies | Formaldehyde killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 1A3 |
| Antibody type and class | IgM |
| Assay System | ELISA and dot ELISA |
| Cross-reactivity | This antibody cross-reacted strongly with strain L20 CPS (serotype 5b) |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals |
| Curator ID | AA + AS |
| Date of Curation | 06-08-2010 |
| References | PMC1263782 |
| PolysacDB ID | 1505 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype b strain 81-750 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues. |
| BCSDB Structure | N/A |
| Proposed functions | LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus |
| Antigenic Nature used to produce antibodies | Formaldehyde killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 1B2 |
| Antibody type and class | IgM |
| Assay System | ELISA and dot ELISA |
| Cross-reactivity | This antibody cross-reacted strongly with strain CPS of serotype 5b |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals |
| Curator ID | AA + AS |
| Date of Curation | 06-08-2010 |
| References | PMC1263782 |
| PolysacDB ID | 1506 |
| Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype b strain 81-750 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Consists of a common backbone consisting of disaccharide repeating units, [->6)-α-DGlcpNAc (1-->5)-β-Kdop-(2-->]n, but, in addition, the CPS of serotype 5b has a lateral β-D-glucopyranosyl residue |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Formaldehyde killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 1B3 |
| Antibody type and class | IgM |
| Assay System | ELISA and dot ELISA |
| Cross-reactivity | This antibody cross-reacted strongly with strain CPS of serotype 5b |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals |
| Curator ID | AA + AS |
| Date of Curation | 07-08-2010 |
| References | PMC1263782 |
| PolysacDB ID | 1507 |
| Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype b strain 81-750 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Consists of a common backbone consisting of disaccharide repeating units, [->6)-α-DGlcpNAc (1-->5)-β-Kdop-(2-->]n, but, in addition, the CPS of serotype 5b has a lateral β-D glucopyranosyl residue |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Formaldehyde killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 1D1 |
| Antibody type and class | IgG3 |
| Assay System | ELISA and dot ELISA |
| Cross-reactivity | This antibody cross-reacted strongly with LPS and CPS of serotype 5a. |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals |
| Curator ID | AA + AS |
| Date of Curation | 07-08-2010 |
| References | PMC1263782 |
| PolysacDB ID | 1508 |
| Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype b strain 81-750 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Consists of a common backbone consisting of disaccharide repeating units, [->6)-α-DGlcpNAc (1-->5)-β-Kdop-(2-->]n, but, in addition, the CPS of serotype 5b has a lateral β-D glucopyranosyl residue |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Formaldehyde killed cells and 2 injections with tetanus toxoid CPS strain L20 conjugate (CPS L20-TT) |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 2B4 |
| Antibody type and class | IgM |
| Assay System | ELISA and dot ELISA |
| Cross-reactivity | This antibody cross-reacted strongly with LPS of serotype 5b |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals |
| Curator ID | AA + AS |
| Date of Curation | 07-08-2010 |
| References | PMC1263782 |
| PolysacDB ID | 1509 |
| Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype b strain 81-750 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Consists of a common backbone consisting of disaccharide repeating units, [->6)-α-DGlcpNAc (1-->5)-β-Kdop-(2-->]n, but, in addition, the CPS of serotype 5b has a lateral β-D-glucopyranosyl residue |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Formaldehyde killed cells and 2 injections with tetanus toxoid CPS strain L20 conjugate (CPS L20-TT) |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 2C3 |
| Antibody type and class | IgG2b |
| Assay System | ELISA and dot ELISA |
| Cross-reactivity | This antibody cross-reacted strongly with LPS and CPS of serotype 5a |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals |
| Curator ID | AA + AS |
| Date of Curation | 07-08-2010 |
| References | PMC1263782 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |