PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us
Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 3

Entry No. - 1   [TOP]
PolysacDB ID2652
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeActinobacillus pleuropneumoniae serotype 7   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodies0.2% formalinized whole cell antigens
Carrier NameN/A
Conjugation MethodN/A
AntibodiesIgM
Antibody type and classMab 7.1.9D4E4
Assay SystemDot-ELISA, ELISA-inhibition test
Cross-reactivityThis mab reacted only with reference strains of A. pleuropneumoniae serotypes 7 and 4. It also cross-reacted strongly with A. lignieresii
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis mab was shown to be suitable for serotyping since they detected 100% of serotype 7 strains
Curator IDAA + AS
Date of Curation26-01-2012
References10223326


Entry No. - 2   [TOP]
PolysacDB ID2653
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeActinobacillus pleuropneumoniae serotype 7   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodies0.2% formalinized whole cell antigens
Carrier NameN/A
Conjugation MethodN/A
AntibodiesIgG3
Antibody type and classMabs 7.1.11C8E3
Assay SystemDot-ELISA, ELISA-inhibition test
Cross-reactivityThis mab reacted only with reference strains of A. pleuropneumoniae serotypes 7
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis mab was shown to be suitable for serotyping since they detected 100% of serotype 7 strains
Curator IDAA + AS
Date of Curation26-01-2012
References10223326


Entry No. - 3   [TOP]
PolysacDB ID2654
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeActinobacillus pleuropneumoniae serotype 7   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodies0.2% formalinized whole cell antigens
Carrier NameN/A
Conjugation MethodN/A
AntibodiesIgM
Antibody type and classMab 7.1.3D5G4
Assay SystemDot-ELISA, ELISA-inhibition test
Cross-reactivityThis mab reacted only with reference strains of A. pleuropneumoniae serotypes 7. It also cross-reacted strongly with A. lignieresii
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis mab was shown to be suitable for serotyping since they detected 100% of serotype 7 strains
Curator IDAA + AS
Date of Curation26-01-2012
References10223326


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020