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| PolysacDB ID | 1122 |
| Carbohydrate Name | O-polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype 1 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The O-polsaccharide structure is as follows : --6)-α-D-Glcp-(1-->2)-α-L-Rhap-(l-->2)-α-L-Rhap-(1--. which is linked to 1-D-GlcpNAc chains on its rhamnopyranosyl residue via 1-->3 linkage. |
| BCSDB Structure | N/A |
| Proposed functions | LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus |
| Antigenic Nature used to produce antibodies | Formalin-fixed A. pleuropneumoniae serotype 1 cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Polysera |
| Antibody type and class | N/A |
| Assay System | ELISA |
| Cross-reactivity | This antibody cross-reacted with serotypes 9 and 11 |
| Proposed epitopes | The epitope was deduced to contain the terminal nonreducing -D-Glc NAc residues |
| IEDB Epitope | N/A |
| Proposed Utility | This antisera not only helped in serotyping analysis but also helped in deducing the epitopes recognized |
| Curator ID | AA + AS |
| Date of Curation | 06-02-2010 |
| References | PMC206369 |
| PolysacDB ID | 1124 |
| Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype 1 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Polysera |
| Antibody type and class | N/A |
| Assay System | ELISA |
| Cross-reactivity | This antibody was specific to serotype 1 only |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | N/A |
| Curator ID | AA + AS |
| Date of Curation | 07-02-2010 |
| References | PMC206369 |
| PolysacDB ID | 1137 |
| Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype 1 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | LMab-1 |
| Antibody type and class | IgM |
| Assay System | ELISA inhibition tests |
| Cross-reactivity | LMAb-1 reacted to only a serotype 1, strain 4074 |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be useful for serotyping studies |
| Curator ID | AA + AS |
| Date of Curation | 13-02-2010 |
| References | 1382625 |
| PolysacDB ID | 1138 |
| Carbohydrate Name | O-polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype 1 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The O-polsaccharide structure is as follows : --6)-α-D-Glcp-(1-->2)-α-L-Rhap-(l-->2)-α-L-Rhap-(1--. which is linked to 1-D-GlcpNAc chains on its rhamnopyranosyl residue via 1-->3 linkage. |
| BCSDB Structure | N/A |
| Proposed functions | LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | LMab-5 |
| Antibody type and class | IgM |
| Assay System | ELISA inhibition tests |
| Cross-reactivity | IMAb-5 reacted with serotype 1, 9 and 11 strains at the same degree and its epitope was found to be located on O-polysaccharide of serotype 1, 9 or 11 lipopolysaccharide (LPS) |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be useful for serotyping studies |
| Curator ID | AA + AS |
| Date of Curation | 13-02-2010 |
| References | 1382625 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |