PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1190
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeYersinia enterocolitica 0:9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe O-antigen part consists of the following residues : -2)-α-D-Rhap4NFo-(1-
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesKilled whole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesYs.T9-6
Antibody type and classIgG3
Assay SystemWhole cell agglutination, immunodiffusion, immunoblotting and ELISA
Cross-reactivityThis Mab was specific to Y. enterocolitica and did not cross-react with Brucella abortus LPS
Proposed epitopesThe epitope was proposed to be partially directed to the core that gave rise to its specificity to Y. enterocolitica. The study also indicates that the portion of the O-antigen recognized is most probably an oligosaccharide portion which encompasses elements of both the O-chain and the core
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used to study the cell wall polysaccharide antigens of other Y. enterocolitica strains and are being evaluated for specific serological identification of B. abortus.
Curator IDAA + AS
Date of Curation02-03-2010
ReferencesPMC261544


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