PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1533
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeKlebsiella pneumoniae strain R20/O1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesHeat-killed Klebsiella pneumoniae strain R20/O1
Carrier NameNil
Conjugation MethodNil
AntibodiesUn-named Mab
Antibody type and classN/A
Assay SystemELISA and immunoblotting
Cross-reactivityThe antibody was able to bind to LPS of clinical isolates of K. pneumoniae, K. oxytoca, K. terrigena and K. planticola but did not bind to LPS of other Gram-negative genera
Proposed epitopesThis Mab recognized the LPS core
IEDB EpitopeN/A
Proposed UtilityThis antibody bound only to those LPS molecules which did not carry an O-antigen and thus this antibody is different from those already published
Curator IDAA + AS
Date of Curation27-08-2010
References11521092


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