PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1042
Carbohydrate NameGlucan   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeurospora crassa   (NCBI Taxonomy)   (Drugpedia)
Basic StructureGlucans are a heterogeneous group of glucose polymers, consisting of a backbone of β(1-->3)-linked β-D-glucopyranosyl units with β(1-->6)-linked side chains of varying distribution and length
BCSDB StructureN/A
Proposed functionsActivates leukocytes, stimulating their phagocytic, cytotoxic, and antimicrobial activities, including the production of reactive oxygen and nitrogen intermediates
Antigenic Nature used to produce antibodiesHomogenous suspension of hyphal walls.
Carrier NameNil
Conjugation MethodNil
AntibodiesS4D1
Antibody type and classIgM
Assay SystemELISA, immunofluorescence
Cross-reactivityThis antibody was cross-reactive with A.nidulans, Schiz.commune.
Proposed epitopes1,3-α-glucan
IEDB EpitopeN/A
Proposed UtilityScreening of fungi for presence of 1,3-α-glucan in hyphae cell wall.
Curator IDAA + AS
Date of Curation13-01-2010
References9245814


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020