PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us
Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1257
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeCampylobacter jejuni serotype O:41 strains   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesPatients infected with Campylobacter jejuni serotype O:41 strains
Carrier NameNil
Conjugation MethodNil
AntibodiesMab SM1-8
Antibody type and classIgM
Assay SystemImmunoblotting
Cross-reactivityThis antibody was specifc to O:41 strains and did not cross-react with any of the other Campylobacter jejuni strains. Also cross-reacted with human GM1 ganglioside
Proposed epitopesThis Mab binds the terminal dissacharide Galβ1-->3GalNAc in the presence of laterally attached N-acetylneuraminic acid [Neu5Ac]
IEDB EpitopeN/A
Proposed UtilityThis Mab will help in the unveiling of the mechanisms of molecular mimicry exhibited by campylobacter LPS with human ganglioside and its functional significance in the disease progression
Curator IDAA + AS
Date of Curation27-04-2010
ReferencesPMC116569


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020