| PolysacDB ID | 2411 |
| Carbohydrate Name | Type 1b polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Streptococcus Group B (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A
|
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | H36B vaccine that had been treated with 2 N acetic acid at 80°C for 10 min to largely desialylate the type lb polysaccharide. |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab SIbD2 |
| Antibody type and class | IgM |
| Assay System | ELISA, indirect immunofluorescence |
| Cross-reactivity | This Mab reacted specifically with the de-sialylated form of the type 1b polysaccharide. This Mab cross-reacts with some oligosaccharides in human milk and certain fetal antigens |
| Proposed epitopes | Lacto-N-tetraose residues seemed to be the immunodominant epitope |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab will help in the development of appropriate vaccines against GBS that would include the possibility of inducing major cross-reactions with human glycoconjugates |
| Curator ID | AA + AS |
| Date of Curation | 03-05-2011
|
| References | 1548081 |