| PolysacDB ID | 1632 |
| Carbohydrate Name | Lipoarabinomannan-B (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe | Mycobacterium leprae (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Mycobacterial lipoarabinomannan is a phosphatidylinositol anchored lipoglycan that consists of an α1-->6 linked backbone, substituted to varying degrees at position 2 with single α-Man residues and directly attached to position 6 of the myo-inositol of a phosphatidylinositol (PI) anchor
|
| BCSDB Structure | N/A |
| Proposed functions | T cell proliferation and to interfere with gamma interferon-mediated activation of macrophages |
| Antigenic Nature used to produce antibodies | Soluble extract of M. leprae |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab SAl.C11H |
| Antibody type and class | IgG1 |
| Assay System | Antigen capture ELISA, direct binding assay, |
| Cross-reactivity | This Mab was specific to M. leprae even though it cross-reacted to a little extent with lipoarabinomannan from M. tuberculosis |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab becomes applicable for monitoring several individual M . Leprae antigens such as lipoarabinomannan |
| Curator ID | AA + AS |
| Date of Curation | 26-09-2010
|
| References | 2467001 |