| PolysacDB ID | 1354 |
| Carbohydrate Name | Tetrasaccharide of 3-deoxy-α-d-manno-oct-2-ulopyranosonic acid (Kdo) (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Chlamydophila psittaci (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Consists of repeating units of tetrasaccharide of 3-deoxy--D-manno-oct-2 ulopyranosonic acid (Kdo) residues
|
| BCSDB Structure | N/A |
| Proposed functions | LPS represents one of the major surface antigens of this microorganism |
| Antigenic Nature used to produce antibodies | Glycoconjugates |
| Carrier Name | Bovine serum albumin |
| Conjugation Method | The allyl glycosides R-OCH2-CH=CH2 were conjugated with cysteamine yielding R-O(CH2)3-S-(CH2)2-NH3+, which were activated with thiophosgene into the isothiocyanate derivatives R O(CH2)3-S-(CH2)2-N=C=S and then conjugated to BSA yielding R-O(CH2)3-S-(CH2)2-NH-CS-NH-BSA, wherein R represents the glycosyl residue |
| Antibodies | Mab S69-4 |
| Antibody type and class | IgG1 |
| Assay System | IFT assay, ELISA |
| Cross-reactivity | This antibody was specific only to C. psittaci |
| Proposed epitopes | The epitope consists of a branched Kdo(2N/A8)[Kdo(2N/A4)] Kdo(2N/A4)Kdo(2N/A4) tetrasaccharide that is specific to Chlamydia psittaci |
| IEDB Epitope | 76909 |
| Proposed Utility | This Mab may provide insight into the molecular details of the interaction of these antibodies with acidic Kdo containing epitopes. Mab S69-4 can be used in immunohistology to reliably identify C. psittaci at the species level |
| Curator ID | AA + AS |
| Date of Curation | 26-06-2010
|
| References | 16282606 |