PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2425
Carbohydrate NameCell wall polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeStreptococcus mutans LM7 Serotype e   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab S3-9
Antibody type and classIgM
Assay SystemRadioimmunoassay, Immunodiffusion tests
Cross-reactivityMab S3-9 reacted with hot-saline extracts of strain LM7, MT703, and P4 (type e) cells but did not react at all with extracts of other S. mutans strains
Proposed epitopesβ-glucosyl moiety of the e-polysaccharide seemed to make up the immunodominant region
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for immunodetection of serotype e Streptococcal cells
Curator IDAA + AS
Date of Curation09-05-2011
ReferencesPMC261049


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