PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1846
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeisseria meningitidis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt consists of a homopolymer of α(2-->8)-linked sialic acid residues
BCSDB Structure10616
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesHuman granulocytes
Carrier NameNil
Conjugation MethodNil
AntibodiesMab My-28
Antibody type and classIgM
Assay SystemELISA, immunoblotting
Cross-reactivityThis Mab reacted with N.meningitidis types 2, 3, 4, 7, 8, and 9
Proposed epitopesLacto-N-neotetraose residue seemed to constitute the epitope
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation14-11-2010
ReferencesPMC258927


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