PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1895
Carbohydrate NameGlucosyl ceramide   (Drugpedia)
Carbohydrate ClassGlycolipid
MicrobeParacoccidiodes brasiliensis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab MEST2
Antibody type and classIgG2a
Assay SystemHigh performance thin layer chromatography immunostaining, solid phase radioimmunoassay
Cross-reactivityThis Mab cross-reacts with glucosyl ceramide from Histoplasma capsulatum, Sporothrix schenckii, Aspergillus fumigatus, Candida albicans, Cryptococcus neoformans, Cryptococcus laurentii and Cryptococcus albidus
Proposed epitopesβ-D-glucose residues and 2-hydroxyl groups in the fatty acid groups seemed to a important part of the epitoipe
IEDB EpitopeN/A
Proposed UtilityThis Mab should act as an effective reagent in studies for the distribution of glycoinositol-phosphoryl ceramides in the plasma membrane of different fungi
Curator IDAA + AS
Date of Curation24-11-2010
References11287397


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