PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1261
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeCampylobacter fetus 554   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen)
BCSDB StructureN/A
Proposed functionsThe LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme
Antigenic Nature used to produce antibodiesA mixture (1:1) of C. fetus 553 and 554 formalin-killed cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab M1183
Antibody type and classIgG1
Assay SystemIndirect ELISA, immunoblotting,
Cross-reactivityThis antibody was specific to O antigen of C. fetus 553 and did not cross-react with C. fetus 554
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used to serotype C. fetus strains
Curator IDAA + AS
Date of Curation02-05-2010
ReferencesPMC98852


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020