| PolysacDB ID | 2639 |
| Carbohydrate Name | Glucurunoxylomannan (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Cryptococcus neoformans Serotype D [strain 24067] (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | A linear α(1-->3)- linked mannan backbone singly substituted with non-reducing β(1-->2) xylose and β(1-->2) glucuronic acid side branches ; O-acetyl groups are present at C-6 of the mannosyl residues
|
| BCSDB Structure | N/A |
| Proposed functions | Antiphagocytic ; an important virulence factor |
| Antigenic Nature used to produce antibodies | Glycoconjugates |
| Carrier Name | Diphtheria toxoid |
| Conjugation Method | 5 mg of GXM (strain 24067) was activated with 5 mg of CDAP (1-cyano-4-dimethylaminopyridinium tetrafluoroborate) and conjugated to Diphtheria toxoid |
| Antibodies | Mab G14 |
| Antibody type and class | IgM |
| Assay System | ELISA and immunofluorescence |
| Cross-reactivity | This antibody cross-reacted with Serotypes A and D |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This MAb mediated complement deposition on solid phase GXM by ELISA |
| Curator ID | AA + AS |
| Date of Curation | 28-07-2011
|
| References | 15271943 |