PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1235
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeBrucella abortus S19   (NCBI Taxonomy)   (Drugpedia)
Basic StructureO-polysaccharide consists of an unbranched linear homopolymer of 10 to 100 α-1,2-linked 4-formamido-4,6-dideoxy-D-mannose (N formylperosamine) residues. The O-polysaccharide is covalently linked to a core oligosaccharide
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesAcetone-killed B. abortus S19 cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab Baps C/Y
Antibody type and classIgG3
Assay SystemEnzyme Immunoassay,immunoblotting
Cross-reactivityThis antibody cross-reacted with Y. enterocolitica 0:9 LPS. Did not cross-react with core oligosaccharide
Proposed epitopesThis Mab recognized the commom [C] epitope of Brucella abortus LPS
IEDB EpitopeN/A
Proposed UtilityThis Mab may help in the elucidation of epitopic distribution of Brucella abortus LPS
Curator IDAA + AS
Date of Curation28-03-2010
ReferencesPMC368229


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020