| PolysacDB ID | 1174 |
| Carbohydrate Name | Lipoologosaccharide band A of the LPS (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Bordetella pertusis 9340 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | B. pertusis LPS is resolved electrophoretically into two bands, a slowly migrating band designated LOS A and a fast-migrating band designated LOS B. These two species differ in molecular weight as three N-acetyl amino sugars found on LOS A are not present on LOS B
|
| BCSDB Structure | N/A |
| Proposed functions | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
| Antigenic Nature used to produce antibodies | N-Lauroyl sarcosine membrane extract (SME) from B. pertussis 9340 |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab BL-4 |
| Antibody type and class | IgG1 |
| Assay System | ELISA,immunoblotting, Antibody accessibility radioimmunoassay, bactericidal asaay, competitive ELISA |
| Cross-reactivity | This antibody reacted with all B.pertusis strains, did not react with B. parapertusis or other gram negative bacteria but cross-reacted with 4 B. bronchiseptica strains which had LOS AB phenotype |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was capable of inducing bactericidal activity in uitro. |
| Curator ID | AA + AS |
| Date of Curation | 25-02-2010
|
| References | 1713258 |