PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2599
Carbohydrate NameUnknown glycoprotein   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeRhizobium leguminosarum   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesPeribacteroid material
Carrier NameNil
Conjugation MethodNil
AntibodiesMab AFRC MAC 64
Antibody type and classN/A
Assay SystemImmunoelectron microscopy
Cross-reactivityThis Mab cross-reacts with the peribacteroid membrane from Pisum sativum, plant plasma membranes and the Golgi bodies, but not the endoplasmic reticulum. This Mab also reacted with peribacteroid membranes from nodules of Vicia and lupin, and with plasma membranes and Golgi membranes from uninfected plant cells, including root tip cells from onion (Allium cepa), indicating that the antigen is highly conserved in the plasma membranes of plant cells
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab should prove useful in characterising the maturation and exchange of material between the Golgi apparatus and the plasma membrane of plant cells in general, quite apart from any specific applications as an immunochemical marker for the peribacteroid membrane in further studies on the Rhizobium-legume interaction
Curator IDAA + AS
Date of Curation15-07-2011
ReferencesPMC554232


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020