PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1250
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeBrucella abortus 2308   (NCBI Taxonomy)   (Drugpedia)
Basic StructureBrucella LPS-PS complexes consist of the Brucella O-chains, native hapten, and polysaccharide B
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole Brucella. Abortus 2308 cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab A
Antibody type and classN/A
Assay SystemImmunoblotting, ELISA, immunoaffinity chromatography, immunoprecipitation,
Cross-reactivityThis antibody was specific to Brucella abortus 2308 strain and did not cross-react with Brucella melitiensis 16M strain and Brucella abortus type 4 strains. It reacted with Brucella abortus 19 strain
Proposed epitopesThis mab was specific to the A epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab would provide a tool to monitor the expression of LPS epitopes by Brucella spp. and determine the content of preparations intended for use in the control of brucellosis
Curator IDAA + AS
Date of Curation08-04-2010
ReferencesPMC267019


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