PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1649
Carbohydrate NameLipoarabinomannan   (Drugpedia)
Carbohydrate ClassGlycolipid
MicrobeMycobacterium leprae   (NCBI Taxonomy)   (Drugpedia)
Basic StructureLipoarabinomannan is a complex carbohydrate containing arabinose, mannose, glycerol, and myo-inositol 1-phosphate, in addition to lactate, succinate, palmitate, and 10 methyloctadecanoate
BCSDB Structure127448
Proposed functionsT cell proliferation and to interfere with gamma interferon-mediated activation of macrophages
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 908
Antibody type and classIgG3
Assay SystemELISA
Cross-reactivityThis Mab cross-reacted with M. tuberculosis
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab would help in the structure elucidation of lipoarabinomanna
Curator IDAA + AS
Date of Curation29-09-2010
ReferencesPMC259992


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020