PolysacDB ID | 1183 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Bordetella pertusis 18530 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A
|
BCSDB Structure | N/A |
Proposed functions | The LOS of B. pertussis exhibits biological activities similar to those of endotoxins from other gram-negative bacteria, including pyrogenicity, toxicity, induction of the Shwartzman reaction, induction of tumor necrosis factor production, and adjuvant properties |
Antigenic Nature used to produce antibodies | B. pertussis 18530 LPS |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 6-4-H6 |
Antibody type and class | IgG3 |
Assay System | ELISA |
Cross-reactivity | This antibody cross-reacted with delipidated polysaccharide fragments (PS-1 and PS-2). did not react with LPS prepared from B. parapertussis and B. bronchiseptica. No cross-reactions were observed with strains of Branhamella catarrhalis, Neisseria meningitidis, Streptococcus miteor, Haemophilus influenza, or Legionella pneumophila |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab might be useful for the detection of soluble antigens and whole bacteria in clinical samples and for studies of the immunochemical structure of B. pertussis LPS. |
Curator ID | AA + AS |
Date of Curation | 27-02-2010
|
References | PMC266249 |