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| PolysacDB ID | 1327 |
| Carbohydrate Name | Unknown carbohydrate (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Candida albicans B311 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 5B2 |
| Antibody type and class | IgM |
| Assay System | ELISA, immunofluorescence, crossed immunoelectrophoresis |
| Cross-reactivity | This antibody cross-reacted with 5 strains of Candida albicans and also cross-reacted with Candida tropicalis and Candida stellatoidia but did not cross-react with T. glabrata and S. cerevisiae |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to isolate surface components and determine the chemical structures that are responsible for the immunological differences. This Mab would facilitate the development of serological assays |
| Curator ID | AA + AS |
| Date of Curation | 13-06-2010 |
| References | PMC259333 |
| PolysacDB ID | 1342 |
| Carbohydrate Name | Phosphopeptidomannan (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Candida albicans (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 5B2 |
| Antibody type and class | N/A |
| Assay System | ELISA, immunoblotting |
| Cross-reactivity | N/A |
| Proposed epitopes | The epitope consists of mannopyranosyl units bound through β(1-->2) linkages present both within the oligomannoside H pool and at the nonreducing end of some oligomannosides A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab helped in epitope elucidation of the mannans present on Candidial surfaces |
| Curator ID | AA + AS |
| Date of Curation | 23-06-2010 |
| References | PMC257398 |
| PolysacDB ID | 1344 |
| Carbohydrate Name | Unknown carbohydrate (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Candida albicans (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Live C. albicans blastoconidia |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 5B2 |
| Antibody type and class | IgM |
| Assay System | Immunofluorescence and precipitin reactions |
| Cross-reactivity | This Mab reacted with C. albicans, C. tropic alis, C. glabr-ata, and C. Giiillierrnondii |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab had the ability to agglutinate Candida species |
| Curator ID | AA + AS |
| Date of Curation | 24-06-2010 |
| References | PMC260140 |
| PolysacDB ID | 2180 |
| Carbohydrate Name | O-polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Salmonella typhimurium (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -2)-α-D-Manp [branched to α-Abep-(1-->3)] -(1-->4)-α-L-Rhap-(1-->3)-α-D-Galp-(1- |
| BCSDB Structure | 6380 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 5B2 |
| Antibody type and class | IgM |
| Assay System | ELISA, immunoblotting, dot blot assay, immunoelectron microscopy |
| Cross-reactivity | This Mab reacted with S. typhimurium (LPS O:1, 4, 5, and 12) while failing to recognize S. typhimurium var. copenhagen (LPS O:1, 4, and 12). It reacted equally with live and heat-attenuated Salmonella B serovars containing LPS O-5 antigen |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to discriminate between S. typhimurium and S. typhimurium var. copenhagen |
| Curator ID | AA + AS |
| Date of Curation | 23-02-2011 |
| References | PMC167767 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |