PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2431
Carbohydrate NameStreptococcus pneumoniae type XIV polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeStreptococcus pneumoniae type XIV   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesHeat killed cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 4AC5
Antibody type and classIgM
Assay SystemHemagglutination, ELISA, Cryoprecipitation and cryoprecipitation-inhibition assays
Cross-reactivityThis Mab cross-reacted with rabbit and human erythrocytes at temperatures below 37°C. This Mab also reacted with phenylLac-BGG
Proposed epitopesThis Mab was specific for N-acetyl-lactosamine, the immunodominant sugar residue expressed on type XIV polysaccharide
IEDB EpitopeN/A
Proposed UtilityThis Mab precipitated at low temperatures and also reacted with rabbit and human erythrocytes at low temperature
Curator IDAA + AS
Date of Curation11-05-2011
References3989304


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