PolysacDB ID | 2167 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Salmonella typhimurium (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -2)-α-D-Manp [branched to α-Abep-(1-->3)] -(1-->4)-α-L-Rhap-(1-->3)-α-D-Galp-(1-
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BCSDB Structure | 124341 |
Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Heated, alcohol-acetone-extracted Sabnonella newport CDC 50 antigen |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 32-1-E3 |
Antibody type and class | IgG3 |
Assay System | Enzyme immunosorbent assay, immunoblotting |
Cross-reactivity | This Mab cross-reacts with Sablonella groups C2 (0:6,8) and C3 (0:-,8) but not with those from any other serogroup tested |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | The MAb agglutinated with all strains of Salmonella serogroups C2 and C3 tested but not with other bacteria. The MAb is useful as a replacement for absorbed, polyclonal, single-factor 0:8 antiserum to discriminate Salmonella serogroups C2 and C3 from serogroup Cl |
Curator ID | AA + AS |
Date of Curation | 17-02-2011
|
References | PMC270587 |