PolysacDB ID | 1242 |
Carbohydrate Name | O-polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Brucella abortus W99 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | O-polysaccharide consists of an unbranched linear homopolymer of 10 to 100 α-1,2-linked 4-formamido-4,6-dideoxy-D-mannose (N formylperosamine) residues. The O-polysaccharide is covalently linked to a core oligosaccharide
|
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Whole B. abortus W99 cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 2C8C4 |
Antibody type and class | IgG3 |
Assay System | ELISA |
Cross-reactivity | This Mab was specific to A strains of Brucella and did not cross-react with Brucella M strain, Y enterocolitica O:9, S-LPSs of S.urbana, Vibrio cholerae and E. coli O:157 |
Proposed epitopes | The epitope was proposed to be a pentasaccharide or larger oligosaccharide composed of α1,2-linked D-Rha4NFo and also contained α1,3 linkages |
IEDB Epitope | N/A |
Proposed Utility | This Mab helped in the epitope strucure elucidation |
Curator ID | AA + AS |
Date of Curation | 04-04-2010
|
References | PMC175246 |