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| PolysacDB ID | 2294 |
| Carbohydrate Name | Core oligosaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella spp. (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen consists of the following residues : -3)-β-D-Quip4NAc-(1-->2)-α-D-Manp [branched to α-L-Rhap-(1-->3)] -(1-->4)-β-D-Galp-(1-->3)-α-D-GlcpNAc-(1- |
| BCSDB Structure | N/A |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Heat killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 2C32E6 |
| Antibody type and class | N/A |
| Assay System | Indirect ELISA |
| Cross-reactivity | This Mab was reactive to S. flexneri and S. boydii |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab has potential importance in immunological detection of Shigella from unknown samples |
| Curator ID | AA + AS |
| Date of Curation | 23-03-2011 |
| References | 11394534 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |