PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us
Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1489
Carbohydrate NameHeptasaccharide motif (M2) of Glucurunoxylomannan   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeCryptococcus neoformans Serotype D [strain 24067]   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe heptasaccharide consists of two M2 triad repeats and mannose residue. The M2 repeat was selected because it is commonly found in GXM of serotype A strains
BCSDB StructureN/A
Proposed functionsGlucurunoxylomannan is an antiphagocytic determinant ; an important virulence factor
Antigenic Nature used to produce antibodiesGlycoconjugates
Carrier NameHuman serum albumin
Conjugation MethodN/A
AntibodiesMab 1H1
Antibody type and classIgA
Assay SystemImmunofluorescence and phagocytosis assays
Cross-reactivityThis antibody cross-reacted with Serotype D
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation02-08-2010
References19464529


Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020