| PolysacDB ID | 2636 |
| Carbohydrate Name | Glucurunoxylomannan (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Cryptococcus neoformans Serotype A (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | A linear α(1-->3)- linked mannan backbone singly substituted with non-reducing β(1-->2) xylose and β(1-->2) glucuronic acid side branches ; O-acetyl groups are present at C-6 of the mannosyl residues
|
| BCSDB Structure | 116826 |
| Proposed functions | Antiphagocytic ; an important virulence factor |
| Antigenic Nature used to produce antibodies | Glycoconjugates |
| Carrier Name | Tetanus toxoid |
| Conjugation Method | Conjugated using CDAP chemistry |
| Antibodies | Mab 13F1 |
| Antibody type and class | IgM |
| Assay System | ELISA |
| Cross-reactivity | This antibody cross-reacted with Serotype A,B,C and D serotypes |
| Proposed epitopes | This Mab did not bind de-O-acetylated GXM suggesting that acetylated residues form an important part of the epitope |
| IEDB Epitope | 115576 |
| Proposed Utility | This antibody was used to decipher and differentiate the serum antibody response of autoimmune mice as compared to normal mice |
| Curator ID | AA + AS |
| Date of Curation | 28-07-2011
|
| References | 1583327 |