PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1694
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
MicrobeMycobacterium avium complex serovar 8   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure109375
Proposed functionsThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 1206.1
Antibody type and classN/A
Assay SystemELISA, Inhibition assays, dot blot
Cross-reactivityN/A
Proposed epitopesN/A
IEDB Epitope76853
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation08-10-2010
ReferencesPMC260783


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