PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1463
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeEnterococcus faecalis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureGlycerol teichoic acid-like molecules with a carbohydrate backbone structure of 6-α-D-glucose- 1-->2 glycerol-3-PO4 with substitution on carbon 2 of the glucose with an α-2-1-D-glucose residue
BCSDB Structure2446
Proposed functionsThese polysaccharides are major virulence factors
Antigenic Nature used to produce antibodiesNil
Carrier NameNil
Conjugation MethodNil
AntibodiesHealthy human sera
Antibody type and classIgG and IgM
Assay SystemELISA
Cross-reactivityThe antisera bound to all 4 serotypes of E. fecalis CPS-A to CPS-D
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThese antibodies promote neutrophil mediated killing
Curator IDAA + AS
Date of Curation24-07-2010
ReferencesPMC1182185


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