PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1201
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeBrucella abortus 1119-3   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesKilled whole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesB.ab.-10
Antibody type and classIgG3
Assay SystemWhole cell agglutination, immunodiffusion, immunoblotting and ELISA
Cross-reactivityThis Mab cross-reacted with LPS and 0-chains of Y. enterocolitica and B. abortus and exhibited high ELISA titers with homologous and heterologous antigens, in addition to agglutinating activity for both bacteria
Proposed epitopesThis Mab was proposed to be directed to antigenic determinants present along the length of the polymeric O-chain
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used to study the cell wall polysaccharide antigens of other Y. enterocolitica strains and are being evaluated for specific serological identification of B. abortus.
Curator IDAA + AS
Date of Curation06-03-2010
ReferencesPMC261544


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