NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Diosgenin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
FasTNF receptor superfamily, member 6355Breast AdenocarcinomaAU565----Diosgenin, a plant-derived steroid, was found to be effective in suppressing FAS expression in HER2-overexpressing breast cancer cells. Diosgenin preferentially inhibited proliferation and induced apoptosis in HER2-overexpressing cancer cells.18022396

 






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