| DB ID | MyCo_7314 |
| Title | The soluble mannose receptor (sMR/sCD206) in critically ill patients with invasive fungal infections, bacterial infections or non-infectious inflammation: a secondary analysis of the EPaNIC RCT |
| Year | 2019 |
| PMID | 31375142 |
| Fungal Diseases involved | Invasive fungal infection |
| Associated Medical Condition | Critically ill patients |
| Genus | None |
| Species | None |
| Organism | None |
| Ethical Statement | The ethics committee of all participating hospitals (ML4190) and the Belgian au-thorities (EudraCT2007e000169e40) approved the study protocol and consent forms that included approval for additional secondary analyses. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | sMR |
| Biomarker Full Name | Soluble serum mannose receptor |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Belgium |
| Cohort | This is a secondary analysis from a multicentre rando-mised controlled trial (n = 4640) investigating the impact of accepting a macronutrient deficit during the first week of critical illness (EPaNIC; ClinicalTrials.gov NCT00512122). Serum sMR concentrations were measured in three matched patient groups (proven/probable IFI, n = 82; bacterial infection, n = 80; non-infectious inflammation, n = 77) on the day of antimicrobial initiation or matched intensive care unit day and the five preceding days, as well as in matched healthy controls (n = 59). |
| Cohort No. | 82 Patients and 59 control |
| Age Group | 60-75 |
| P Value | p<0.02 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | None |
| Analysis Method | None |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | None |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
