| DB ID | MyCo_7292 |
| Title | Exploratory Research for New Diagnostic Markers of Mucormycosis |
| Year | 2024 |
| PMID | 38825527 |
| Fungal Diseases involved | Mucormycosis |
| Associated Medical Condition | None |
| Genus | Rhizopus |
| Species | oryzae |
| Organism | Rhizopus oryzae |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Urine |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | CotH3-1 |
| Biomarker Full Name | Spore coat protein CotH3-1 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Japan |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Mucormycosis is a deep-seated mycosis caused by fungi belonging to the order Mucorales, represented by Rhizopus oryzae, and is known as one of the most lethal diseases, occurring mainly in patients with hematologic malignancies. Diagnosis is difficult due to its relative rarity, limited testing methods, and similarities in patient background and clinical symptoms with invasive pulmonary aspergillosis (IPA). |
| Technique | None |
| Analysis Method | None |
| ELISA kits | diagnostic kit by Enzyme-linked immuno-sorbent assay (ELISA) using a monoclonal antibody against Rhizopus specific antigen (RSA) |
| Assay Data | None |
| Validation Techniques used | None |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
