MycoBiomDB – Record Details (MyCo_7171)

Biomarker Record Details

Database ID: MyCo_7171
DB IDMyCo_7171
TitleSoluble CD14 and toll-like receptor-2 are potential salivary biomarkers for oral lichen planus and burning mouth syndrome
Year2008
PMID17916440
Fungal Diseases involvedOral candidiasis
Associated Medical ConditionOral lichen planus and burning mouth syndrome
GenusCandida
Speciesspp.
OrganismCandida spp.
Ethical StatementInformed consent was obtained from all subjects in accordance with the Indiana University’s institutional review board.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSaliva
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamesTLR-2
Biomarker Full NamesTLR-2
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortThe study group consisted of individuals examined by Dr. Susan Zunt at the dental faculty private practice clinics of the Indiana University School of Dentistry (IUSD). The study cohort included a total of 45 subjects with the following clinical distribution: 25 with OLP, 10 with BMS and 10 OLP/BMS patients with co-existent OC.
Cohort No.45
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodWestern blotting
ELISA kitssandwich ELISA kit (R&D systems)
Assay DataNone
Validation Techniques usedWestern blotting, ELISA, qRT-PCR
Up Regulation Down RegulationUp regulated
Sequence DataNone
External LinkNone