MycoBiomDB – Record Details (MyCo_7151)

Biomarker Record Details

Database ID: MyCo_7151
DB IDMyCo_7151
TitleBronchoalveolar lavage triacetylfusarinine C (TAFC) determination for diagnosis of invasive pulmonary aspergillosis in patients with hematological malignancies
Year2017
PMID28576596
Fungal Diseases involvedInvasive pulmonary aspergillosis
DiseaseAspergillosis (Aspergillus Infection)
Associated Medical ConditionHematological malignancies
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementNone
Site of InfectionUnspecified
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBronchoalveolar lavage fluid (BALF)
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameTAFC
Biomarker Full NameTriacetylfusarinine C
Biomarker TypeDiagnostic
BiomoleculeSiderophore
Geographical LocationAustria
CohortA total of 45 BALF samples obtained from 45 patients with underlying hematological malignancies (15 patients with proven or probable IA and 30 controls with no IPA who were each matched 2:1 by age and underlying diseases) were included in this analysis.
Cohort No.15 Patients and 30 control
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive Value1
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
Sub TechniqueELISA
TechniqueImmunoassay
Analysis MethodSerum GM Platelia assay
ELISA kitsNone
Assay DataNone
Validation Techniques usedNone
Up Regulation Down RegulationPositive
Sequence DataNone