MycoBiomDB – Record Details (MyCo_7113)

Biomarker Record Details

Database ID: MyCo_7113
DB IDMyCo_7113
TitleSerum (1,3)-beta-D-glucan is an inefficient marker of breakthrough candidemia
Year2014
PMID25349254
Fungal Diseases involvedCandidemia
Associated Medical ConditionNone
GenusCandida
Specieskrusei
OrganismCandida krusei
Ethical StatementThis investigation was approved by the Human Ethics Review Committee of Toranomon Hospital.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeNegative
BiomoleculeProtein
Geographical LocationJapan
CohortDuring the study period, a total of 147 cases of candidemia were identified, and 31 patients met the criteria for breakthrough candidemia. Serum BDG levels were measured in 25 patients with breakthrough candidemia and 67 patients with nonbreakthrough candidemia.
Cohort No.147
Age Group22-95
P Valuep=.01
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodWako turbidimetric assay
ELISA kitsNone
Assay DataNone
Validation Techniques usedWako turbidimetric assay
Up Regulation Down RegulationNegative
Sequence DataNone
External LinkNone