MycoBiomDB – Record Details (MyCo_7037)

Biomarker Record Details

Database ID: MyCo_7037
DB IDMyCo_7037
TitleAirway epithelial phosphoinositide 3-kinase-δ contributes to the modulation of fungi-induced innate immune response
Year2017
PMID29622694
Fungal Diseases involvedAlternaria alternata infection
DiseaseAlternaria Infection
Associated Medical ConditionNone
GenusAlternaria
Speciesalternata
OrganismAlternaria alternata
Ethical StatementAll animal experiments were approved by the Institutional Animal Care and Use Committee of the Chonbuk National University and were performed in accordance with the ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines.
Site of InfectionUnspecified
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtracted Lungs tissue
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NamePhosphoinositide 3-kinase (PI3K)-δ
Biomarker Full NamePhosphoinositide 3-kinase (PI3K)-δ
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationSouth Korea
CohortFemale C57BL/6 mice, 8–10 weeks of age, were used.
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
Sub TechniqueElectrophoresis
TechniqueInstrument-based
Analysis MethodWestern blot analysis
ELISA kitsNone
Assay DataNone
Validation Techniques usedWestern blot analysis
Up Regulation Down RegulationPositive
Sequence DataNone