| DB ID | MyCo_6954 |
| Title | Serum Sphingolipids Aiding the Diagnosis of Adult HIV-Negative Patients with Talaromyces marneffei Infection |
| Year | 2021 |
| PMID | 34262882 |
| Fungal Diseases involved | Talaromyces marneffei infection |
| Disease | Talaromycosis |
| Associated Medical Condition | None |
| Genus | Talaromyces |
| Species | marneffei |
| Organism | Talaromyces marneffei |
| Ethical Statement | The studies involving human participants were reviewed and approved by the Ethics Committee of the First Affiliated Hospital of Guangzhou Medical University (ethical approval number: 2019-26). |
| Site of Infection | Unspecified |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | Sa (d16:0) (SPLs) |
| Biomarker Full Name | Sphinganine (d16:0) (Sphingolipids) |
| Biomarker Type | Diagnostic |
| Biomolecule | Lipid |
| Geographical Location | China |
| Cohort | A total of 33 patients and 13 healthy controls (Control group) were enrolled. |
| Cohort No. | 33 Patients and 13 control |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Sub Technique | HPLC |
| Technique | Mass Spectrometry |
| Analysis Method | UHPLC-MS based Sphingolipidomic Analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | UHPLC-MS based Sphingolipidomic Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
