| DB ID | MyCo_6525 |
| Title | Pulmonary cryptococcosis: Clinical, radiographical and serological markers of dissemination |
| Year | 2008 |
| PMID | 18339023 |
| Fungal Diseases involved | Pulmonary cryptococcosis |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | neoformans |
| Organism | Cryptococcus neoformans |
| Ethical Statement | The institu-tional review board approved this study. (Chang Gung Memorial Hospital, Taoyuan, Taiwan) |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | sCRAG |
| Biomarker Full Name | Serum cryptococcal antigen |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Taiwan |
| Cohort | There were 31 patients (14 male) identified with pulmonary cryptococcosis in the study period. |
| Cohort No. | 31 |
| Age Group | None |
| P Value | p= 0.001 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Cryptococcosis is a rare granulomatous disease caused by the encapsulated yeast Cryptococcus neo-formans that enters the human body through inhala- tion. The infection is usually systemic and typically presents as meningitis which has a mortality rate of up to 80% in immunocompromised hosts. |
| Technique | Assay |
| Analysis Method | sCRAG titres Assay |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | sCRAG titres Assay, CXR Assay |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
