MycoBiomDB – Record Details (MyCo_6520)

Biomarker Record Details

Database ID: MyCo_6520
DB IDMyCo_6520
TitleA one-year longitudinal evaluation of cerebrospinal fluid and blood neurochemical markers in a patient with cryptococcal meningitis complicated by ischemic stroke
Year2021
PMID34923332
Fungal Diseases involvedCryptococcal meningitis
DiseaseCryptococcosis (Cryptococcus Infection)
Associated Medical ConditionNone
GenusCryptococcus
Speciesneoformans
OrganismCryptococcus neoformans
Ethical StatementNone
Site of InfectionUnspecified
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceCerebrospinal fluid (CSF)
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamesNfL
Biomarker Full NameNeurofilament light chain protein
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationGermany
CohortA 33-year-old HIV-negative patient was admitted to our departmentwith acute left hemiparesis and hypoesthesia progressing in 5 h.
Cohort No.1
Age Group33
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
Sub TechniqueELISA
TechniqueImmunoassay
Analysis MethodSingle molecule array (Simoa) technology
ELISA kitsELISA Kit (Euroimmun AG, Lübeck, Germany)
Assay DataNone
Validation Techniques usedSingle molecule array (Simoa) technology
Up Regulation Down RegulationIncrease
Sequence DataNone