MycoBiomDB – Record Details (MyCo_6416)

Biomarker Record Details

Database ID: MyCo_6416
DB IDMyCo_6416
TitlePathogen specific cytokine release reveals an effect of TLR2 Arg753Gln during Candida sepsis in humans
Year2008
PMID18249133
Fungal Diseases involvedCandida sepsis
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtracted DNA
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameTLR2 SNP Arg753Gln
Biomarker Full NameTLR2 SNP Arg753Gln
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationGermany
CohortIn this study, 325 posttraumatic patients with sepsis and septic shock were collected over a period of 4 years. Over a ten-month period, 47 of these 325 patients were monitored daily during their treatment in the anesthesiological intensive care unit (ICU) of the University Hospital Ulm, Germany.
Cohort No.47
Age Group57.3 ± 10.4
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueBioinformatics analysis
Analysis MethodPyrosequencing Analysis
ELISA kitsNone
Assay DataNone
Validation Techniques usedPyrosequencing Analysis, Human cytokine Lincoplex assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone