| DB ID | MyCo_6146 |
| Title | Proteomic demonstration of the recurrent presence of inter-alpha-inhibitor H4 heavy-chain during aspergillosis induced in an animal model |
| Year | 2013 |
| PMID | 24360996 |
| Fungal Diseases involved | Invasive pulmonary aspergillosis |
| Disease | Aspergillosis (Aspergillus Infection) |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | This protocol was based on the animal model approved by the ethics committee for animal experimenta-tion of Val-de-Loire (France). |
| Site of Infection | Unspecified |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Bronchoalveolar lavage fluid (BALF) |
| Host Group | Animal |
| Host Common name | Rat |
| Host Scientific name | Rattus norvegicus |
| Biomarker Name | ITIH4 |
| Biomarker Full Name | Inter-alpha-inhibitor H4 heavy-chain |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | France |
| Cohort | 7 six- to eight-week-old male Sprague-Dawley rats (Janvier®) were immunocompro- mised by repeated intraperitoneal injections of cyclophosphamide (Endoxan® BaxterTM). |
| Cohort No. | None |
| Age Group | None |
| P Value | p<0.01 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Sub Technique | LC-MS + Computational |
| Technique | Hybrid Methods |
| Analysis Method | Proteomics Approach |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Proteomics Approach |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
