| DB ID | MyCo_6106 |
| Title | Development stage-specific proteomic profiling uncovers small, lineage specific proteins most abundant in the Aspergillus Fumigatus conidial proteome |
| Year | 2012 |
| PMID | 22545825 |
| Fungal Diseases involved | Aspergillus fumigatus infection |
| Disease | Aspergillosis (Aspergillus Infection) |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | None |
| Site of Infection | Unspecified |
| Opportunistic invasive | None |
| Sample type | Extracted Conidia |
| Sample source | Extracted conidia |
| Host Group | NA |
| Host Common name | NA |
| Host Scientific name | NA |
| Biomarker Name | CipC family protein |
| Biomarker Full Name | CipC family protein |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Aspergillus fumigatus is the most common airborne fungal pathogen, which can infect ever increasing numbers of patients with lung disease, immune system disorders or undergoing immunosuppression therapy. In patients with asthma and cystic fibrosis, it can cause allergic diseases like allergic bronchopulmonary aspergil-losis. In immunosuppressed individuals such as leukemia and bone marrow transplant patients, inhalation of A. fumigatus conidia (asexual spores) can cause invasive aspergillosis (IA), a life-threatening disease, which is dif- ficult to diagnose and treat. |
| Sub Technique | LC-MS + Computational |
| Technique | Hybrid Methods |
| Analysis Method | Proteomics Approach |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Proteomics Approach |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
