| DB ID | MyCo_5713 |
| Title | Dual roles of CD40 on microbial containment and the development of immunopathology in response to persistent fungal infection in the lung |
| Year | 2010 |
| PMID | 20864680 |
| Fungal Diseases involved | Cryptococcal infection |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | neoformans |
| Organism | Cryptococcus neoformans |
| Ethical Statement | Experiments were approved by the Animal Care and Use Committee at the University of Michigan. |
| Site of Infection | Lungs |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Extracted Lungs tissue |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | CD40 |
| Biomarker Full Name | CD40 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | CD40 / mice (B6.129P2-Cd40tm1Kik/J) and wild type (CD40 / ) mice (C57BL/6J), used as control, were pur- chased from The Jackson Laboratory (Bar Harbor, ME). Mice were housed at the University of Michigan Unit for Laboratory Animal Medicine facilities (Ann Arbor, MI), which is fully accredited by the American Association for Accreditation of Laboratory Animal Care. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Flow Cytometry Analysis, qRT-PCR |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
