MycoBiomDB – Record Details (MyCo_5695)

Biomarker Record Details

Database ID: MyCo_5695
DB IDMyCo_5695
TitlePolymorphisms in Receptors Involved in Opsonic and Nonopsonic Phagocytosis, and Correlation with Risk of Infection in Oncohematology Patients
Year2018
PMID30275011
Fungal Diseases involvedFungal infection
Associated Medical ConditionNone
GenusCandida
Speciesspp.
OrganismCandida spp.
Ethical StatementThe study protocol for patients was approved by the ethical review committees of both hospitals, Hospital Universitario Río-Hortega (HURH) and the Hospital Clínico Universitario of Valladolid (HCUV).
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtracted RNA
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamePTX3
Biomarker Full NamePentraxin-3
Biomarker TypeDiagnostic
BiomoleculeGene
Geographical LocationSpain
CohortThis is a retrospective study of a group of 198 patients with high-risk hemato-logical malignancies enrolled between 2013 and 2017 from both the Hospital Universitario Río Hortega (HURH) and the Hospital Clínico Universitario of Valladolid (HCUV). A retrospective study was carried out with 198 oncohematology patients.
Cohort No.198
Age Group4–92
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniquePCR
Analysis MethodqRT-PCR
ELISA kitsNone
Assay DataNone
Validation Techniques usedqRT-PCR
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone