| DB ID | MyCo_5637 |
| Title | Circulating microRNA sequencing revealed miRNome patterns in hematology and oncology patients aiding the prognosis of invasive aspergillosis |
| Year | 2021 |
| PMID | 33735827 |
| Fungal Diseases involved | Allergic bronchopulmonary aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | This study design and protocol were approved by the Institutional Review Board of the Faculty of Human Medicine, Zagazig University. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Plasma |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | miRNA-132 |
| Biomarker Full Name | miRNA-132 |
| Biomarker Type | Diagnostic/Prognostic |
| Biomolecule | miRNA |
| Geographical Location | Egypt |
| Cohort | A total of 30 controls, 30 allergic asthmatic patients, 30 severe asthma with fungal sensitization (SAFS) patients, and 30 ABPA patients were included. |
| Cohort No. | 90 Patients and 30 Control |
| Age Group | None |
| P Value | p<0.001 |
| Sensitivity | 0.867 |
| Specificity | 0.8 |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | RayBio® Human IL-5 ELISA Kit according to the manufacturer’s protocol (catalog no.: ELH- IL5; RayBiotech, Parkway, GA, USA). |
| Assay Data | None |
| Validation Techniques used | qRT-PCR, ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
